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10 day Panama Travel Itinerary

This 10 day Panama travel itinerary takes you through the vibrant capital of Panama City, the serene and culturally rich San Blas Islands, the adventurous highlands of Boquete, and the tropical paradise of Bocas del Toro. It’s a perfect blend of urban exploration, pristine beaches, lush mountains, and Caribbean charm for a diverse and memorable journey.

Currency

Panamanian Balboa (PAB) and USD are used interchangeably. 1 USD = 1 PAB.

Local Language

Spanish is the official language; English is widely spoken in tourist areas.

Visa Requirements

Visa-free for stays up to 180 days for USA, UK, Canada, EU, Australia & NZ citizens.

Expense Level

$$ (mid-range affordability).

Plug Type

Type A and B sockets; 110V.

Safety

Generally safe; use caution in sketchy areas of Panama City and remain vigilant in remote regions.

Vaccination

Yellow fever vaccine required for travelers from risk areas; hepatitis A and typhoid recommended.

Payment

Cards are widely accepted in cities, but carry cash for remote areas like San Blas.

Nightlife

Vibrant in Panama City and Bocas del Toro.

Best Months to Visit

December to April (dry season); Carnival in February is a famous annual event.

Climate

Tropical; pack light clothing and a rain jacket for occasional showers.

Water Safety

Not safe to drink; stick to bottled water.

Tipping

10-15% in restaurants; optional elsewhere.

Cultural Etiquette

Greet warmly, and avoid political discussions.

Emergency Numbers

Police: 104, Ambulance: 911.

Time Zone

GMT-5 (Eastern Standard Time).

Panama City Itinerary

Overview

This 10 day Panama travel itinerary begins in Panama City. It is the vibrant capital that blends history and modernity. From the colonial charm of Casco Viejo to the engineering marvel of the Panama Canal, it offers a mix of culture, history, and urban adventure.

10 day Panama Travel Itinerary
Panama City’s vibrant financial district

How long to stay in Panama City

2 days

How to get to Panama City:

Arrive at Tocumen International Airport (PTY). Taxi or Uber to the city center costs $25 (30 minutes).

Best hotels to stay in Panama City

  • Selina Casco Viejo: Stylish hostel in the heart of the historic district. Book here.
  • Luna’s Castle Hostel: Budget-friendly option with a social vibe. Book here.
  • Hotel Casa Panama: Boutique hotel with colonial charm and a rooftop pool. Book here.
Best Hotels to stay in Panama City
Selina, Casco Viejo.

What to do in Panama City

  • Visit the Panama Canal Visitor Center at Miraflores Locks ($20).
  • Explore the colonial charm of Casco Viejo (Free).
  • Walk or bike along the scenic Amador Causeway (Free).
  • Admire biodiversity exhibits at the Biomuseo ($18).
  • Hike Ancon Hill for panoramic views of the city (Free).
  • Stroll the vibrant Cinta Costera, perfect for jogging or relaxing (Free).
Panama Canal Visitor Center
The Panama Canal Visitor Center

Where to eat in Panama City

  • El Trapiche: Authentic Panamanian cuisine ($$); Google Rating: 4.5.
  • Mercado de Mariscos: Fresh ceviche and seafood ($); Google Rating: 4.3.
  • Maito: Modern Panamanian dishes ($$$); Google Rating: 4.7.
Where to eat in Panama City
Crispy steak and rondom fish at Maito

Modes of transport in Panama City

  • Public buses (Metro Card required; top up at stations).
  • Uber and taxis are widely available and safe.
  • Walking is great for exploring Casco Viejo and the Cinta Costera.

Panama City digital nomad rating

4/5.
Pros: Reliable internet, coworking spaces, great food scene.
Cons: Heavy traffic and limited green spaces outside urban parks.
More on Nomadlist.

San Blas Islands Itinerary

Overview

This 10 day Panama travel itinerary includes the San Blas Islands, a pristine archipelago of over 350 islands managed by the Guna Yala indigenous people. With crystal-clear waters, vibrant coral reefs, and untouched beaches, it’s a perfect blend of nature and culture.

San Blas Islands Itinerary
Wonderful view point of The San Blas Islands

How long to stay in San Blas Islands

3 days

How to get from Panama City to San Blas Islands

  • Step 1: Book a 4×4 shuttle service from Panama City to the San Blas port (3 hours; $30-$40).
  • Step 2: From the port, take a boat transfer to your chosen island (30-45 minutes; $20-$25).
  • Note: Your accommodation often includes transport arrangements—confirm in advance.

Best accommodations in San Blas Islands

  • Franklin Island: A budget-friendly option offering basic cabins and stunning beaches. Book here.
  • Iguana Island Lodge: Private bungalows with upgraded amenities. Book here.
  • Yandup Island Lodge: Boutique eco-lodge with exceptional service and meals included. Book here.
 yandup island lodge
Yandup island lodge

What to do in San Blas Islands:

  • Relax on pristine beaches and soak in the serene atmosphere (Free).
  • Snorkel to explore colorful coral reefs and marine life ($10).
  • Take a boat tour to nearby islands for even more scenic beauty (prices vary).
  • Learn about Guna Yala culture through village tours and handicraft shopping ($20).

Where to eat in San Blas Islands

Meals are typically included with your accommodations. Expect simple yet delicious local dishes, including fresh fish and coconut rice.

Modes of transport in San Blas Islands

  • Boats are the only mode of transport between islands. Arrange transfers through your accommodation or tour operator.

San Blas Islands digital nomad rating

2/5.
Pros: Stunning natural environment, unique cultural experience.
Cons: Limited or no Wi-Fi, making it unsuitable for work..

Boquete Itinerary

Overview

This 10 day Panama travel itinerary continues in Boquete, nestled in the Chiriquí Highlands. Known for its cool climate, lush landscapes, and thrilling outdoor adventures, it’s a haven for nature lovers with attractions ranging from coffee plantations to cloud forests.

Boquete Itinerary
Boquete, Panama

How long to stay in Boquete

2 days

How to get from San Blas Islands to Boquete

  • Return to Panama City via boat and 4×4 shuttle.
  • From Panama City, take an overnight bus to David (8 hours; $15).
  • From David, take a local bus or taxi to Boquete (1 hour; $5-$10).

Best hotels to stay in Boquete

  • Hostal Gaia: Budget-friendly, centrally located hostel with a friendly vibe. Book here.
  • Bambuda Castle: A quirky, mid-range option with stunning views and a pool. Book here.
  • Hotel Panamonte: A luxurious boutique hotel steeped in history. Book here.
Best hotels to stay in Boquete
Bambuda Castle

What to do in Boquete

  • Visit a coffee plantation for a guided tour and tasting ($35).
  • Hike the Sendero Los Quetzales trail, a stunning route through cloud forests (Free).
  • Relax in the Caldera Hot Springs, surrounded by natural beauty ($5).
  • Zipline through the Boquete Tree Trek for an adrenaline rush ($65).
  • Take a dip in the Lost Waterfalls during a picturesque hike ($10).
What to do in Boquete
Visit coffee plantations on a guided tour

Where to eat in Boquete

  • Big Daddy’s Grill: Casual seafood and tacos ($$); Google Rating: 4.6.
  • Sugar & Spice: Popular for breakfast, sandwiches, and baked goods ($); Google Rating: 4.8.
  • The Rock: Upscale dining in a cozy setting with a fireplace ($$$); Google Rating: 4.7.
Big Daddy’s Grill
Smoky ribs from Big Daddy’s Grill

Modes of transport in Boquete

  • Local buses connect nearby areas and are very affordable.
  • Taxis and rental cars are available for more flexibility.
  • Walking is ideal within the town center.

Boquete digital nomad rating

4/5.
Pros: Good internet, serene environment, excellent coffee shops for work.
Cons: Limited coworking spaces and nightlife.

Bocas del Toro Itinerary

Overview

This 10 day Panama travel itinerary concludes in Bocas del Toro, a lively Caribbean archipelago known for its turquoise waters, vibrant nightlife, and diverse outdoor activities. It’s the ultimate destination for relaxation and adventure to end your Panama journey.

Bocas del Toro Itinerary
Explore the vibrant beauty of Bocas del Toro

How long to stay in Bocas del Toro

3 days

How to get from Boquete to Bocas del Toro

  • Step 1: Take a shuttle from Boquete to Almirante (4 hours; $30).
  • Step 2: From Almirante, take a water taxi to Bocas Town on Isla Colón (30 minutes; $6).
  • Alternative: Flights are available from David to Bocas del Toro (1 hour; $100 one-way) for a faster option.

Best hotels to stay in Bocas del Toro

  • Selina Bocas del Toro: A social hostel with waterfront views and great events. Book here.
  • Hostal Hansi: Affordable and quiet, with clean and comfortable rooms. Book here.
  • Hotel Bocas del Toro: A boutique hotel with excellent service and sea views. Book here.
Best hotels to stay in Bocas del Toro
Selina Bocas del Toro

What to do in Bocas del Toro

  • Relax on Starfish Beach, a tranquil spot with calm waters and plenty of starfish (Free).
  • Take a boat tour to Dolphin Bay, where bottlenose dolphins play in their natural habitat ($25).
  • Snorkel or dive at Cayo Coral, known for its vibrant marine life and coral reefs ($30).
  • Visit Red Frog Beach for a mix of lush forest trails and pristine sands ($10).
  • Explore Bastimentos National Marine Park, a haven for wildlife and beautiful beaches ($10 entry).
What to do in Bocas del Toro
Snorkel at Cayo Coral

Where to eat in Bocas del Toro

  • El Ultimo Refugio: Upscale Caribbean-inspired seafood ($$$); Google Rating: 4.6.
  • Capitán Caribe: Local food truck offering fresh, delicious Caribbean street food ($); Google Rating: 4.8.
  • Bibi’s on the Beach: Relaxed beachfront dining with fresh seafood and cocktails ($$); Google Rating: 4.5.
Bibi's On The Beach
Bibi’s On The Beach

Modes of transport in Bocas del Toro

  • Water taxis are the primary mode of transport between islands, costing $2-$5 for short rides.
  • Rent bicycles to explore Isla Colón or hire a golf cart for convenience.
  • Walking is great within Bocas Town itself.

Bocas del Toro digital nomad rating

4.5/5.
Pros: Reliable internet in town, vibrant digital nomad community, and stunning scenery.
Cons: Limited coworking spaces outside of Bocas Town, and some islands lack connectivity.
More on Nomadlist.

Extend your trip

Extend your 10 day Panama travel itinerary by joining it to the Two Week Costa Rica Travel Itinerary. Travel from Bocas del Toro to Puerto Viejo de Talamanca by boat and shuttle (4–5 hours, $30–40 USD), crossing the border at Sixaola. This scenic route connects you directly to Costa Rica’s Caribbean coast. You can formally begin your Two Week Costa Rica Travel Itinerary by traveling from Puerto Viejo de Talamanca to San José. Take the MEPE bus (4–5 hours, $12–15 USD) or a shuttle service (4.5 hours, $30–50 USD).

What do you think?

Have tips to share, questions to ask, or your own travel stories? Leave a comment below and help shape the perfect itinerary!

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